Droperidol vs prochlorperazine for the treatment of acute headache

Autor: Edward J. Brizendine, Carey D. Chisholm, Christopher S. Weaver, Geoffrey G. Somerville, William H Cordell, James B. Jones, Michael J Foley, Beverly K. Giles
Rok vydání: 2002
Předmět:
Zdroj: The Journal of emergency medicine. 26(2)
ISSN: 0736-4679
Popis: To determine if droperidol i.v. is as effective as prochlorperazine i.v. in the emergency department (ED) treatment of uncomplicated headache, a randomized, controlled, blinded study was conducted in the Emergency Departments of two urban teaching hospitals. Patients >or= 18 years old with crescendo-onset headache were eligible for inclusion. Ninety-six patients (48 in each group) were randomized to receive droperidol 2.5 mg i.v. or prochlorperazine 10 mg i.v. Baseline characteristics were similar between the two study groups. For the main study outcome, 83.3% in the droperidol group and 72.3% in the prochlorperazine group reported 50% pain reduction at 30 min (p
Databáze: OpenAIRE