Association between allergic responses and Schistosoma mansoni infection in residents in a low-endemic setting in Brazil
| Autor: | Teiliane Rodrigues Carneiro, Marta Cristhiany Cunha Pinheiro, Fernando Schemelzer de Moraes Bezerra, José Ajax Nogueira Queiroz, Sara Menezes de Oliveira |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Microbiology (medical)
Hypersensitivity Immediate Allergy lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Antibodies Helminth Schistosomiasis Parasite load Feces Antigen parasitic diseases Medicine Animals Humans Inverse correlation Parasite Egg Count Skin Tests biology business.industry Schistosoma mansoni Eosinophil Allergens Immunoglobulin E biology.organism_classification medicine.disease Schistosomiasis mansoni Infectious Diseases medicine.anatomical_structure Parasitic disease Antigens Helminth Case-Control Studies Immunology Parasitology business Brazil |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 6, Pp 770-774 (2014) Revista da Sociedade Brasileira de Medicina Tropical v.47 n.6 2014 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT Revista da Sociedade Brasileira de Medicina Tropical, Volume: 47, Issue: 6, Pages: 770-774, Published: DEC 2014 |
| ISSN: | 1678-9849 |
| Popis: | Introduction Schistosomiasis is endemic in 76 countries and territories. Several studies have found an inverse correlation between parasitic disease and the development of allergies. The purpose of the present study was to determine whether infection with Schistosoma mansoni in subjects with a low parasite load is protective against allergy. The final sample consisted of 39 S. mansoni-positive and 52 S. mansoni-negative residents of a small community in northeastern Brazil. Methods All subjects were submitted to the Kato-Katz test, anti-S. mansoni IgG measurement, the prick test for aeroallergens, eosinophil counts and serum IgE measurement. Results Subjects who reacted to one or more antigens in the prick test were considered allergic. Only 7 S. mansoni-positive subjects (17.9%) reacted to one or more antigens, whereas 20 S. mansoni-negative subjects (38.5%) tested positive for allergy. Conclusions Our findings suggest that, in areas of low endemicity, infection with S. mansoni significantly reduces the risk of the development of allergy in subjects with a low parasite load. |
| Databáze: | OpenAIRE |
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