Iron-promoted free radical cascade difunctionalization of unsaturated benzamides with silanes

Autor: Jincan Zhao, Yaxin Ge, Qinqin Yan, Yunfei Tian, Jilai Wu, Zejiang Li, Luping Zheng, Yingming Ren
Rok vydání: 2020
Předmět:
Zdroj: Chemical Communications. 56:12656-12659
ISSN: 1364-548X
1359-7345
DOI: 10.1039/d0cc05213b
Popis: Iron salt/peroxide promoted cascade difunctionalization of unsaturated benzamides with silanes has been reported. It provides a convenient, highly selective, and efficient protocol for the synthesis of various silylated dihydroisoquinolinones and 1,3-isoquinolinediones. In particular, the present methodology only gives cyclization products in good isolated yields under the typical conditions.
Databáze: OpenAIRE