Development of anodic titania nanotubes for application in high sensitivity amperometric glucose and uric acid biosensors
| Autor: | Li-Fan Zhang, Tai-Ping Sun, Jyh-Ling Lin, Hsiang-Ching Lee, Yuan-Lung Chin |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Materials science
titania nanotubes (TNTs) Conductometry Inorganic chemistry Transducers Enzyme electrode Nanoparticle chemistry.chemical_element Metal Nanoparticles Carbon nanotube Biosensing Techniques amperometry glucose uric acid (UA) lcsh:Chemical technology Biochemistry Sensitivity and Specificity Article Analytical Chemistry law.invention chemistry.chemical_compound law lcsh:TP1-1185 Electrical and Electronic Engineering Instrumentation Electrodes Titanium Anodizing Reproducibility of Results Equipment Design Atomic and Molecular Physics and Optics Amperometry Uric Acid Equipment Failure Analysis Glucose chemistry Biosensor Ethylene glycol |
| Zdroj: | Sensors (Basel, Switzerland) Sensors, Vol 13, Iss 10, Pp 14161-14174 (2013) Sensors; Volume 13; Issue 10; Pages: 14161-14174 |
| ISSN: | 1424-8220 |
| Popis: | The purpose of this study was to develop novel nanoscale biosensors using titania nanotubes (TNTs) made by anodization. Titania nanotubes were produced on pure titanium sheets by anodization at room temperature. In this research, the electrolyte composition ethylene glycol 250 mL/NH4F 1.5 g/DI water 20 mL was found to produce the best titania nanotubes array films for application in amperometric biosensors. The amperometric results exhibit an excellent linearity for uric acid (UA) concentrations in the range between 2 and 14 mg/dL, with 23.3 (µA·cm−2)·(mg/dL)−1 UA sensitivity, and a correlation coefficient of 0.993. The glucose biosensor presented a good linear relationship in the lower glucose concentration range between 50 and 125 mg/dL, and the corresponding sensitivity was approximately 249.6 (µA·cm−2)·(100 mg/dL)−1 glucose, with a correlation coefficient of 0.973. |
| Databáze: | OpenAIRE |
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