| Autor: |
Chuang‐Jia Hu, Yan‐Wei Wang, Wei‐Xing Huang, Yu‐Bin Xia |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
ESC heart failureReferences. |
| ISSN: |
2055-5822 |
| Popis: |
The progression of atherosclerosis can lead to the occurrence of multiple cardiovascular diseases (coronary heart disease, etc.). E prostanoid receptor-3 (EP3) is known to participate in the progression of atherosclerosis. This study aimed to investigate the mechanism by which EP3 modulates the development of atherosclerosis.ApoEEP3 inhibitor alleviates ox-LDL-induced HASMC inflammation via mediation of cAMP/PKA/CREB/IL-17/ICAM-1 axis. Our study might shed new lights on discovering novel strategies against atherosclerosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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