Clicking the brain into deep sleep. Commentary on Weigenandet al. ()

Autor:	Maurice Göldi, Thomas Schreiner
Rok vydání:	2017
Předmět:	0301 basic medicine thalamocortical system medicine.medical_specialty Cognitive Neuroscience General Neuroscience slow oscillations MEDLINE Brain Sleep in non-human animals memory 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Physical medicine and rehabilitation medicine sleep Psychology spindles Neuroscience 030217 neurology & neurosurgery Slow-wave sleep
Zdroj:	The European Journal of Neuroscience
ISSN:	0953-816X
DOI:	10.1111/ejn.13494
Popis:	The application of auditory clicks during non‐rapid eye movement (NREM) sleep phase‐locked to the up state of the slow oscillation (closed‐loop stimulation) has previously been shown to enhance the consolidation of declarative memories. We designed and applied sequences of three clicks during deep NREM sleep to achieve a quasi‐phase‐dependent open‐loop stimulation. This stimulation was successful in eliciting slow oscillation power in the stimulation period. Although fast and slow spindle power were markedly decreased during the stimulation period, memory consolidation did not differ from control. During putative up states fast spindle power remained, however, at control levels. We conclude that concurrence of slow oscillations and fast spindles suffices to maintain memory consolidation at control levels despite an overall decreased spindle activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89608199f8e560578364b26261e42f89 https://doi.org/10.1111/ejn.13494 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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