Twelve-year outcome of patients with an abnormal exercise radionuclide left ventricular angiogram and angiographically insignificant coronary artery disease
| Autor: | Timothy F. Christian, Todd D. Miller, Raymond J. Gibbons, John H. Haley, David O. Hodge, Amir Lerman |
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| Rok vydání: | 1998 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Population Coronary Disease Coronary Angiography Revascularization Disease-Free Survival Coronary artery disease Ventricular Dysfunction Left Surveys and Questionnaires Internal medicine medicine Humans cardiovascular diseases Angiocardiography Myocardial infarction Circumflex education Radionuclide Ventriculography education.field_of_study Ejection fraction medicine.diagnostic_test business.industry Vascular disease Middle Aged medicine.disease Exercise Test cardiovascular system Cardiology Female Radiology Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | The American Journal of Cardiology. 82:418-422 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/s0002-9149(98)00352-x |
| Popis: | This study examines the long-term prognosis of patients with an abnormal exercise radionuclide angiogram in the absence of significant angiographic coronary artery disease (CAD). In general, patients without significant CAD have an excellent prognosis, but the long-term outcome for the subset of patients with an "ischemic" exercise test is not known. In this study, 161 patients with normal coronary arteries or insignificant CAD (50% left main and70% left anterior descending, left circumflex, or right), resting left ventricular (LV) ejection fractionor = 0.50, and an abnormal exercise radionuclide angiogram (LV ejection fraction that decreased with exercise or peak exercise LV ejection fraction0.60) were followed for a median duration of 11.3 years. The mean delta LV ejection fraction was -0.07, 98 patients (61%) had a decrease in LV ejection fraction ofor = 5 units, and 40 patients (25%) had peak exercise LV ejection fraction0.50. During follow-up there were 19 deaths (only 1 of which was cardiac), 7 nonfatal myocardial infarctions, and 9 revascularization procedures. At 12 years, overall survival was 88%, better than the expected survival for the age- and sex-matched general population. Survival free of cardiac death or myocardial infarction was 94% and survival free of any cardiac event including revascularization was 88%. Thus, patients with an abnormal exercise radionuclide angiogram but without significant CAD have an excellent long-term prognosis. |
| Databáze: | OpenAIRE |
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