Trends in upper gastro-intestinal cancer among the elderly in Denmark, 1980-2012
| Autor: | Per Pfeiffer, Mette Andersen, Michael Bau Mortensen, Merete Krogh, K R Schønnemann, Eva Holtved |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Intestinal Neoplasms/epidemiology Esophageal Neoplasms Esophageal Neoplasms/epidemiology Denmark Comorbidity 03 medical and health sciences 0302 clinical medicine Age Distribution Stomach Neoplasms Internal medicine Intestinal Neoplasms Intestine Small medicine Humans Radiology Nuclear Medicine and imaging Registries Sex Distribution Survival rate Cause of death Aged Aged 80 and over Relative survival business.industry Mortality rate Incidence (epidemiology) Incidence Stomach Neoplasms/epidemiology Cancer Hematology General Medicine Esophageal cancer medicine.disease Denmark/epidemiology Surgery Cancer registry Survival Rate Oncology 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Female business |
| Zdroj: | Schønnemann, K R, Mortensen, M B, Krogh, M, Holtved, E, Andersen, M M S, Pfeiffer, P & Academy of Geriatric Cancer Research (AgeCare) 2016, ' Trends in upper gastro-intestinal cancer among the elderly in Denmark, 1980-2012 ', Acta Oncologica, vol. 55, no. Suppl. 1, pp. 23-28 . https://doi.org/10.3109/0284186X.2015.1114673 |
| ISSN: | 1651-226X |
| DOI: | 10.3109/0284186X.2015.1114673 |
| Popis: | Background Upper gastro-intestinal cancer (UGIC) includes malignancies in esophagus, stomach and small intestine, and represents some of the most frequent malignancies worldwide. The aim of the present analysis was to describe incidence, mortality and survival in UGIC patients in Denmark from 1980 to 2012 according to differences in age and time periods.Material and methods UGIC was defined as ICD-10 codes C15-C17. Data derived from the NORDCAN database with comparable data on cancer incidence mortality, prevalence and relative survival in the Nordic countries, where the Danish data were delivered from the Danish Cancer Registry and the Danish Cause of Death Registry with follow-up for death or emigration until the end of 2013.Results The proportion of male patients over the age of 70 years diagnosed with esophageal cancer was constant over time (around 42%) but increased in females to 49% in 2012. Incidence rates increased with time and continued to rise in all ages. Mortality rates were clearly separated by age groups with increasing mortality rates by increasing age group for both sexes. Relative survival increased slowly over time in all age groups. The proportion of older male and female patients with stomach cancer increased to 50% and 54%, respectively, in 2012. Incidence rates decreased steadily with time, especially from 1980 to 1990 but continued to decrease in all age groups. Mortality rates decreased considerably from 1980 to 90 and have been almost constant during the last decade for both women and men. Relative survival increased modest over time in both genders and all age groups. In 2012, only 1471 persons were alive after a diagnosis of stomach cancer.Conclusion There is a need for clinical trials focusing on patients over the age of 70 years with co-existing comorbidity. |
| Databáze: | OpenAIRE |
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