A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis
| Autor: | Jamie McMahon, Jacina Walker, Arifuzzman Khan, Michael Kirk, Gulam Khandaker, Nicolas R. Smoll |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
RNA viruses
Viral Diseases Household contact Epidemiology Attack rate Social Sciences medicine.disease_cause Pathology and Laboratory Medicine Pediatrics Families Medical Conditions Sociology Medicine and Health Sciences Human Families Child Children Child care Multidisciplinary Gastroenteritis Infectious Diseases Medical Microbiology Child Preschool Viral Pathogens Gastroenteritis outbreak Viruses Medicine Pathogens Pediatric Infections Infants Research Article medicine.medical_specialty Growth phase Science Gastroenterology and Hepatology Microbiology Caliciviruses Infectious Disease Epidemiology medicine Humans Microbial Pathogens Biology and life sciences business.industry Norovirus Organisms Outbreak Infant Calicivirus Infection Age Groups People and Places Population Groupings business Demography |
| Zdroj: | PLoS ONE, Vol 16, Iss 11 (2021) PLoS ONE PLoS ONE, Vol 16, Iss 11, p e0259145 (2021) |
| ISSN: | 1932-6203 |
| Popis: | There is a large burden of norovirus disease in child-care centers in Australia and around the world. Despite the ubiquity of norovirus outbreaks in child-care centers, little is known about the extent of this burden within the child-care center and the surrounding household clusters. Therefore, we performed an in-depth analysis of a gastroenteritis outbreak to examine the patterns of transmissions, household attack rates and the basic reproduction number (R0) for Norovirus in a child-care facility. We used data from parental interviews of suspected cases sent home with gastroenteritis at a child-care center between 24th of August and 18th of September 2020. A total of 52 persons in 19 household clusters were symptomatic in this outbreak investigation. Of all transmissions, 23 (46.9%) occurred in the child-care center, the rest occurring in households. We found a household attack rate of 36.5% (95% CI 27.3, 47.1%). Serial intervals were estimated as mean 2.5 ± SD1.45 days. The R0, using time-dependent methods during the growth phase of the outbreak (days 2 to 8) was 2.4 (95% CI 1.50, 3.50). The count of affected persons of a child-care center norovirus outbreak is approximately double the count of the total symptomatic staff and attending children. In the study setting, each symptomatic child-care attendee likely infected one other child-care attendee or staff and just over one household contact on average. |
| Databáze: | OpenAIRE |
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