Neurologic and Radiologic Manifestations of Three Girls Surviving Acute Carbon Monoxide Poisoning
| Autor: | Y. L. Chan, Wing-kwan Alex Leung, WL Yeung, Winnie C.W. Chu, Albert M. Li, Chi-hang Assunta Ho, Kam Lun Hon |
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| Rok vydání: | 2006 |
| Předmět: |
Time Factors
Visual acuity Adolescent Vision Disorders Computed tomography medicine.disease_cause Basal Ganglia Carbon Monoxide Poisoning 03 medical and health sciences 0302 clinical medicine Basal ganglia medicine Humans Survivors 030212 general & internal medicine Child Confusion Cerebral Cortex Fluorodeoxyglucose medicine.diagnostic_test Carbon monoxide poisoning business.industry Oxygen Inhalation Therapy 030208 emergency & critical care medicine Magnetic resonance imaging Cerebral Infarction medicine.disease Treatment Outcome Positron emission tomography Positron-Emission Tomography Anesthesia Acute Disease Pediatrics Perinatology and Child Health Female Neurology (clinical) medicine.symptom Tomography X-Ray Computed business Nasal cannula medicine.drug |
| Zdroj: | Journal of Child Neurology. 21:737-741 |
| ISSN: | 1708-8283 0883-0738 |
| DOI: | 10.1177/08830738060210090401 |
| Popis: | We report the neurologic and radiologic manifestations of three adolescent girls with acute carbon monoxide poisoning. The girls were found collapsed and unconscious in a bathroom where liquid petroleum gas was being used as heating fuel. As hyperbaric oxygen therapy was not available locally, they only received oxygen supplementation via nasal cannula (4 L/minute) as treatment in the first 2 days. On transfer to a tertiary center in Hong Kong, evolving neurologic manifestations of visual acuity and field deficits, confusion, and focal motor weaknesses were observed. Focal infarctions were evident in cerebral computed tomography in one patient and cortical lesions on magnetic resonance imaging in all three patients. [18F]Fluorodeoxyglucose (FDG) positron emission tomography (PET) revealed additional decreased metabolism in the basal ganglia in two patients, which was typical of carbon monoxide poisoning. The neurologic deficits resolved completely at 3 weeks after the exposure, but psychologic symptoms succeeded. This report serves to alert clinicians to the varied neuro-ophthalmologic manifestations and psychologic impairment even with the same duration of carbon monoxide poisoning. PET might be more sensitive in detecting cerebral injuries specific for carbon monoxide poisoning. (J Child Neurol 2006;21:737—741; DOI 10.2310/7010.2006.00172). |
| Databáze: | OpenAIRE |
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