mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal

Autor: Isabel Henriques, Elmano Ramalheira, Pedro Teixeira, Rafael D.S. Tavares, Inês Roxo, Marta Tacão, Sonia Maria Soares Ferreira
Rok vydání: 2017
Předmět:
0301 basic medicine
Epidemiology
Polymyxin
Antibiotics
lcsh:Medicine
Drug resistance
medicine.disease_cause
Plasmid
gene
carbapenem
meropenem
colistin
polymixin
fluconazole
linezolid
co-resistance
antimicrobial resistance
antibacterial
antibiotic
fluconazole
polycyclic compounds
IncX4::mcr-1
IncF::Tn1441d-blaKPC-3
sequence type
Escherichia coli ST744
Klebsiella pneumoniae
multiresistance
Portugal
bacteria
Escherichia coli Infections
Escherichia coli Proteins
co-resistance
Anti-Bacterial Agents
3. Good health
Infectious Diseases
Gene
carbapenem
meropenem
colistin
polymixin
medicine.drug
Microbiology (medical)
Genotype
medicine.drug_class
030106 microbiology
linezolid
Microbial Sensitivity Tests
Biology
Serogroup
Meropenem
beta-Lactamases
lcsh:Infectious and parasitic diseases
Microbiology
03 medical and health sciences
Drug Resistance
Bacterial
Research Letter
Escherichia coli
medicine
Humans
lcsh:RC109-216
mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy
Portugal
Portugal
Colistin
lcsh:R
biochemical phenomena
metabolism
and nutrition
bacterial infections and mycoses
antibacterial
antimicrobial
bacteria
Thienamycins
MCR-1
Zdroj: Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 23, Iss 8, Pp 1419-1421 (2017)
ISSN: 1080-6059
1080-6040
DOI: 10.3201/eid2308.170162
Popis: Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-blaKPC-3, already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance to carbapenems and polymyxins after therapy with drugs from both classes.
Databáze: OpenAIRE
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