Sibling rivalry versus mother's curse: can kin competition facilitate a response to selection on male mitochondria?
| Autor: | Thomas A. Keaney, Heidi W. S. Wong, Luke Holman, Damian K. Dowling, Therésa M. Jones |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
Male Mitochondrial DNA Non-Mendelian inheritance Sibling rivalry (animals) Offspring Evolution media_common.quotation_subject Kin selection Biology 010603 evolutionary biology 01 natural sciences General Biochemistry Genetics and Molecular Biology Competition (biology) 03 medical and health sciences Behavioral ecology Animals Selection Genetic Selection (genetic algorithm) 030304 developmental biology General Environmental Science media_common Genetics 0303 health sciences General Immunology and Microbiology Siblings fungi General Medicine Mitochondria Drosophila melanogaster Haplotypes Female Maternal Inheritance General Agricultural and Biological Sciences |
| Zdroj: | Proc Biol Sci |
| Popis: | Assuming that fathers never transmit mitochondrial DNA (mtDNA) to their offspring, mitochondrial mutations that affect male fitness are invisible to direct selection on males, leading to an accumulation of male-harming alleles in the mitochondrial genome (mother's curse). However, male phenotypes encoded by mtDNA can still undergo adaptation via kin selection provided that males interact with females carrying related mtDNA, such as their sisters. Here, using experiments withDrosophila melanogastercarrying standardized nuclear DNA but distinct mitochondrial DNA, we test whether the mitochondrial haplotype carried by interacting pairs of larvae affects survival to adulthood, as well as the fitness of the adults. Although mtDNA had no detectable direct or indirect genetic effect on larva-to-adult survival, the fitness of male and female adults was significantly affected by their own mtDNA and the mtDNA carried by their social partner in the larval stage. Thus, mtDNA mutations that alter the effect of male larvae on nearby female larvae (which often carry the same mutation, due to kinship) could theoretically respond to kin selection. We discuss the implications of our findings for the evolution of mitochondria and other maternally inherited endosymbionts. |
| Databáze: | OpenAIRE |
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