Bronchoscopy in neonates with severe bronchopulmonary dysplasia in the NICU
| Autor: | Joseph Piccione, Erik A. Jensen, Erik B. Hysinger, Huayan Zhang, Nicholas Friedman |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Neonatal intensive care unit Bronchoalveolar Lavage 03 medical and health sciences 0302 clinical medicine Bronchoscopy Intensive Care Units Neonatal medicine Humans 030212 general & internal medicine Bronchopulmonary Dysplasia Retrospective Studies Philadelphia Tracheobronchomalacia Bacteria medicine.diagnostic_test business.industry Ipratropium Infant Newborn Obstetrics and Gynecology Bethanechol medicine.disease Anti-Bacterial Agents Bronchoalveolar lavage 030228 respiratory system Tracheomalacia Anesthesia Pediatrics Perinatology and Child Health Female Bronchomalacia Complication business Airway Bronchoalveolar Lavage Fluid |
| Zdroj: | Journal of Perinatology. 39:263-268 |
| ISSN: | 1476-5543 0743-8346 |
| DOI: | 10.1038/s41372-018-0280-y |
| Popis: | To describe the findings, resulting changes in management, and safety profile of flexible bronchoscopy in the neonates with severe bronchopulmonary dysplasia. This was a retrospective case series of twenty-seven neonates with severe bronchopulmonary dysplasia who underwent flexible bronchoscopy in the neonatal intensive care unit. Flexible bronchoscopy revealed airway pathology in 20/27 (74%) patients. Tracheomalacia 13/27 (48%), bronchomalacia 11/27 (40.7%), and airway edema 13/27 (48%) were the most common findings. Bronchoalveolar lavage (BAL) was performed in 17 patients. BAL culture revealed a microorganism in 12/17 (70.5%) cases. Findings from bronchoscopy resulted in change in clinical management in 17/27 (63%) patients. Common interventions included initiation of antibiotics (37%) and treatment of tracheobronchomalacia with bethanechol (22.2%), atrovent (18.5%), and PEEP titration (18.5%). Bronchoscopy was performed without significant complication in 26/27 (97%) patients. Flexible bronchoscopy can be a safe and useful tool for the management of neonates with severe bronchopulmonary dysplasia. |
| Databáze: | OpenAIRE |
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