Movement-related cortical activation in familial Parkinson disease
| Autor: | Luc Defebvre, X. Douay, Alain Destée, J. L. Bourriez, Arnaud Delval, N. Waucquiez, Philippe Derambure, E. Labyt |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Movement Disorders business.industry Motor Cortex Parkinson Disease Disease Audiology Middle Aged medicine.disease Central nervous system disease Degenerative disease medicine Reaction Time Humans Female Neurology (clinical) Cortical Synchronization business Neuroscience Familial disease Aged |
| Zdroj: | Neurology. 67(6) |
| ISSN: | 1526-632X |
| Popis: | We sought to determine whether or not first-degree relatives of patients with familial Parkinson disease (FDRs) present impaired movement-related cortical activity. We studied 10 familial Parkinson disease subjects, 10 FDRs, and 10 controls and analyzed event-related mu desynchronization (ERD) and beta synchronization. Forty percent FDRs presented reduced premovement mu ERD latency, suggesting that premovement cortical activation is impaired in FDRs. |
| Databáze: | OpenAIRE |
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