Induction of antimicrobial activity of some macromycetes by low-intensity light

Autor: N. L. Poyedinok, O. B. Mykhaylova, A. M. Negriyko, I. A. Dudka, B. F. Vasilyeva, O. V. Efremenkova
Jazyk: ruština
Rok vydání: 2015
Předmět:
Zdroj: Biotechnologia Acta, Vol 8, Iss 1, Pp 63-79 (2015)
ISSN: 2410-776X
2410-7751
Popis: 63 Bacteremia is an actual problem of modern medicine. In recent years a great number of human pathogenic bacteria with drug resistance was found [1]. As a result the number of effective antimicrobial drugs decreases and there is an increasing need in new antibiotics [2, 3]. There are many antibiotic producers among proand eukaryotes, but fungi, including higher fungi, can be considered as the largest group of producers which was studied for the last decade [4–11]. However, the investigations of antimicrobial activity of macromycetes are limited by the screening and determination of chemical structure of antibiotics. One of the requirements to antibiotic producers is submerged cultivation that in case of discovery of the promising compound can be a base for technology development and its production by synthesis. To reach higher productivity of the processes that would result in the receipt of the target product researchers are looking for optimum conditions of cultivation. The study of factors that affect antimicrobial activity of macromycetes is limited by selection of nutrient media [12, 13]. Despite the great amount of investigations the search of new environmentally friendly regulators of growth and biological activity of fungi is highly relevant. The light is one of such regulators [14–16]. We have previously shown the possibility of the usage of lowintensity coherent laser and incoherent light from different sources to stimulate the growth and biosynthetic activity of some macromycetes [17]. UDC 544.431.122:582.284.3:628.93 doi: 10.15407/biotech8.01.063
Databáze: OpenAIRE