Evaluation, management and outcome of upper urinary tract transitional cell carcinoma – A five year single center experience
| Autor: | Arvind Nayak, Prasad Mylarappa, Sandeep Puvvada, D Ramesh, Avinash B. Patil |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
recurrence business.industry renal tumors lcsh:R lcsh:Medicine medicine.disease Single Center Surgery upper tract transitional cell carcinoma medicine.anatomical_structure Transitional cell carcinoma Ureter Median follow-up transitional cell carcinoma Concomitant ureteric tumors Medicine Stage (cooking) General Agricultural and Biological Sciences business Renal pelvis Upper urinary tract |
| Zdroj: | Asian Journal of Medical Sciences, Vol 7, Iss 3, Pp 84-88 (2016) |
| ISSN: | 2091-0576 2467-9100 |
| DOI: | 10.3126/ajms.v7i3.13894 |
| Popis: | Aims and Objectives: To review a single centre experience in the evaluation, management and outcome of upper tract transitional cell carcinoma. Materials and Methods: We reviewed 18 cases over five years from January 2010 to October 2015 with a median follow up of 18 months. Patient characteristics including age, sex, symptoms and signs were reviewed. All patients were evaluated with ultrasound and contrast enhanced computerized tomography. Tumour details including location, laterality, grade and stage was noted based on pathological findings.Results: The mean age of the patients included was 57 years. Most common presentation was haematuria (72%). Most common location of the tumours was renal pelvis (50%), followed by ureter (39%) and tumours in both renal pelvis and ureter in 11%. Concomitant bladder involvement was seen in 17% of the patients. Nephroureterectomy with excision of bladder cuff was the most common surgery performed (78%). 11% of the patients underwent renal sparing surgery and two other patients underwent nephroureterocystoprostatectomy. Morbidity rate was 22% and recurrence was seen in 16% of the patientsConclusion: Transitional cell carcinoma of the upper tract is a rare tumour which is known for its multicentricity and recurrence. . Nephroureterectomy with excision of bladder cuff has been the gold standard for the management, although endosurgical and tumour sparing surgery in selected cases have proven to be equally efficacious. Tumour grade and surgical procedure performed are independent risk factors for recurrence.Asian Journal of Medical Sciences Vol. 7(3) 2016 84-88 |
| Databáze: | OpenAIRE |
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