Heterogeneity of AmpC Cephalosporinases of Hafnia alvei Clinical Isolates Expressing Inducible or Constitutive Ceftazidime Resistance Phenotypes

Autor:	Samuel Bellais, Patrice Nordmann, Laurent Poirel, Amal Karim, Delphine Girlich, Thierry Naas
Rok vydání:	2000
Předmět:	Molecular Sequence Data Ceftazidime Microbial Sensitivity Tests Biology beta-Lactamases Microbiology Plasmid Mechanisms of Resistance Genetic variation polycyclic compounds medicine Humans Pharmacology (medical) Amino Acid Sequence Gene Cephalosporinase Fenoterol Antibacterial agent Pharmacology Genetics Sequence Homology Amino Acid Nucleic acid sequence Genetic Variation Drug Resistance Microbial Hafnia alvei biochemical phenomena metabolism and nutrition bacterial infections and mycoses Hafnia biology.organism_classification Phenotype Electrophoresis Gel Pulsed-Field Infectious Diseases Genes Bacterial bacteria Plasmids medicine.drug
Zdroj:	Antimicrobial Agents and Chemotherapy. 44:3220-3223
ISSN:	1098-6596 0066-4804
DOI:	10.1128/aac.44.11.3220-3223.2000
Popis:	Ten unrelated Hafnia alvei clinical isolates were grouped according to either their low-level and inducible cephalosporinase production or their high-level and constitutive cephalosporinase production phenotype. Their AmpC sequences shared 85 to 100% amino acid identity. The immediate genetic environment of ampC genes was conserved in H. alvei isolates but was different from that found in other ampC -possessing enterobacterial species.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892bae3ef448f2c544c89167bed9f0a5 https://doi.org/10.1128/aac.44.11.3220-3223.2000 Zobrazit plný text záznamu