beta-2-microglobulin in benign and malignant adnexal skin tumors and metastasizing basocellular carcinomas
| Autor: | Matti Kallioinen, K. Dammert |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Sebaceous gland
Pathology medicine.medical_specialty Histology Skin Neoplasms Beta-2 microglobulin Dermatology Biology Hair follicle medicine.disease Skin Diseases Pathology and Forensic Medicine Staining Immunoenzyme Techniques medicine.anatomical_structure Carcinoma Basal Cell Sweat gland medicine Immunohistochemistry Humans Basal cell carcinoma Neoplasm Metastasis beta 2-Microglobulin Immunostaining |
| Zdroj: | Journal of cutaneous pathology. 11(1) |
| ISSN: | 0303-6987 |
| Popis: | Immunostaining for beta-2-microglobulin (beta-2m) was performed on various benign and malignant adnexal skin tumors and 3 cases of metastasizing basocellular carcinomas. All the tumors and their metastases, with the exception of 2 basocellular carcinomas gave evidence of beta-2m. Most tumors contained both stained and unstained cells. The stained cells showed differentiation, the unstained ones appeared to be undifferentiated and basal-like in character. The staining of cutaneous tumors for beta-2m may offer a tool for investigating tumor differentiation, but seems not to be of much value in distinguishing malignant from benign lesions. |
| Databáze: | OpenAIRE |
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