In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope
| Autor: | Eric D. Cocker, Benjamin A. Flusberg, Erik P. Anderson, Juergen C. Jung, Mark J. Schnitzer |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Endoscopes
Optical fiber Materials science Miniaturization business.industry Equipment Design Image plane Image Enhancement Fluorescence Hippocampus Atomic and Molecular Physics and Optics law.invention Equipment Failure Analysis Mice Optics Microscopy Fluorescence Multiphoton law Microscopy Medical imaging Fluorescence microscope Animals business Refractive index Photonic crystal |
| Zdroj: | Optics letters. 30(17) |
| ISSN: | 0146-9592 |
| Popis: | We introduce a compact two-photon fluorescence microendoscope based on a compound gradient refractive index endoscope probe, a DC micromotor for remote adjustment of the image plane, and a flexible photonic bandgap fiber for near distortion-free delivery of ultrashort excitation pulses. The imaging head has a mass of only 3.9?g and provides micrometer-scale resolution. We used portable two-photon microendoscopy to visualize hippocampal blood vessels in the brains of live mice. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|