B-N-acetyl hexosaminidase (B-NAH) serum levels after endotoxin administration into the portal vein in the rat
| Autor: | E Scapa, J. Sayfan, Abramovici J, Eshchar J, Ruben Orda, Neuman M |
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| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
Time Factors medicine.drug_class Kupffer Cells Portal vein digestive system Bile Acids and Salts Hexosaminidase B Internal medicine medicine Animals Hexosaminidase chemistry.chemical_classification Hepatology Bile acid Common bile duct business.industry Portal Vein Kupffer cell Cell Membrane beta-N-Acetylhexosaminidases Rats Endotoxins Enzyme medicine.anatomical_structure Endocrinology chemistry Female business Ligation |
| Zdroj: | Liver. 11(1) |
| ISSN: | 0106-9543 |
| Popis: | — Endotoxin was injected directly into the portal vein in rats with and without common bile duct (CBD) ligation. B-N-acetyl hexosaminidase (B-NAH) activity levels in the serum were found to be significantly elevated 24 h later in both groups. Serum bile acid levels were found to be significantly higher in the endotoxin-injected groups of rats compared to controls. Thus, endotoxin, as well as bile acids, may cause damage to Kupffer cell membranes, resulting in accumulation of B-NAH in rat serum. |
| Databáze: | OpenAIRE |
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