Spontaneous Human Myometrial Contractility in the Third Trimester of Pregnancy in Relation to Past Mode of Delivery
| Autor: | Gillian A. Ryan, Denis J. Crankshaw, Sarah M. Nicholson, John J. Morrison |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Human myometrium Pregnancy Trimester Third Third trimester Tissue Culture Techniques Uterine Contraction 03 medical and health sciences 0302 clinical medicine Pregnancy 030225 pediatrics medicine Humans Cesarean delivery Myometrial contractility 030219 obstetrics & reproductive medicine Cesarean Section Vaginal delivery Obstetrics business.industry Obstetrics and Gynecology medicine.disease Parity Mode of delivery Pediatrics Perinatology and Child Health Myometrium Female business Maximum amplitude |
| Zdroj: | American Journal of Perinatology. 38:126-130 |
| ISSN: | 1098-8785 0735-1631 |
| DOI: | 10.1055/s-0039-1694980 |
| Popis: | Objective It is well established that women with a previous vaginal delivery have higher success rates in relation to vaginal birth after cesarean than those without. The aim of this study was to examine the effect of past mode of delivery on contractile parameters of human myometrium in vitro. Study Design Myometrial strips were excised from 64 women at cesarean delivery (CD) and recordings of spontaneous contractile activity analyzed and compared across three clinical groups: (1) women with no previous delivery (Group 1); (2) women with CD only (Group 2); and (3) women with a history of vaginal delivery and CD (Group 3). Results Myometrial samples from women in Group 3, women who had a previous vaginal delivery, had a significantly greater maximum amplitude of contractions (p Conclusion Many of the functional parameters of human uterine contractions are altered, or enhanced, in the women who have had a previous vaginal delivery, when compared with those without. This may partly explain the clinical differences observed in labor. |
| Databáze: | OpenAIRE |
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