Role of anticoagulation in lowering the mortality in hospitalized covid-19 patients

Autor:	Muhammad, Aamir Waheed, Khalid, Rashid, Tawfik, Rajab, Ahmad, Rajab, Adnan H, Adnan, Harris, Fayyaz, Ahmad A, Ibad, Rabia, Basri, Yahya, Khan, Habib I, Alhabib, Abdelnaser, Elzouki
Rok vydání:	2022
Předmět:	SARS-CoV-2 Thromboembolism Anticoagulants Humans Venous Thromboembolism General Medicine Blood Coagulation COVID-19 Drug Treatment
Zdroj:	Saudi Medical Journal. 43:541-550
ISSN:	1658-3175 0379-5284
DOI:	10.15537/smj.2022.43.6.20220046
Popis:	To reducing the risk of venous thromboembolic (VTE) events and subsequent mortality in covid-19 patients is still a matter of research. This systematic review and meta-analysis serve the purpose of comparing the mortality associated with the intensity of anticoagulation in patients admitted with covid-19.A total of 7120 patients were recruited in 11 studies comparing using prophylactic anticoagulants against therapeutic anticoagulants.Our study showed that using prophylactic anticoagulants was associated with a 42% reduction in mortality compared to therapeutic anticoagulants (OR 0.58 (95% CI:0.676-0.499),Our meta-analysis favors using prophylactic anticoagulation in covid-19 patients reduces all-cause mortality in comparison to therapeutic anticoagulation however the impact on mortality when compared with no anticoagulation was not significant.PROSPERO Number: CRD42021257320.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890adcd5f88dd8f41cb018e33257f3e4 https://doi.org/10.15537/smj.2022.43.6.20220046 Zobrazit plný text záznamu