Iron Supplementation Influence on the Gut Microbiota and Probiotic Intake Effect in Iron Deficiency—A Literature-Based Review
| Autor: | Ioana Moroșan, Carmen Pop, Andreea Diana Kerezsi, Ioana Rusu, Carmen Ioana Mureșan, Oana Lelia Pop, Ramona Suharoschi, Magdalena Istrati, Romana Vulturar, Sonia Socaci, Anca Fărcaș, Dan Cristian Vodnar |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Antioxidant Synbiotics medicine.medical_treatment Biological Availability Literature based lcsh:TX341-641 Review Biology Gut flora law.invention 03 medical and health sciences Probiotic iron law medicine Humans Food science Organism 030109 nutrition & dietetics Nutrition and Dietetics Anemia Iron-Deficiency gut microbiota Metabolism biology.organism_classification Gastrointestinal Microbiome 030104 developmental biology probiotics Dietary Supplements Iron supplementation diet prebiotics lcsh:Nutrition. Foods and food supply Iron Dietary Food Science |
| Zdroj: | Nutrients, Vol 12, Iss 1993, p 1993 (2020) Nutrients |
| ISSN: | 2072-6643 |
| Popis: | Iron deficiency in the human body is a global issue with an impact on more than two billion individuals worldwide. The most important functions ensured by adequate amounts of iron in the body are related to transport and storage of oxygen, electron transfer, mediation of oxidation-reduction reactions, synthesis of hormones, the replication of DNA, cell cycle restoration and control, fixation of nitrogen, and antioxidant effects. In the case of iron deficiency, even marginal insufficiencies may impair the proper functionality of the human body. On the other hand, an excess in iron concentration has a major impact on the gut microbiota composition. There are several non-genetic causes that lead to iron deficiencies, and thus, several approaches in their treatment. The most common methods are related to food fortifications and supplements. In this review, following a summary of iron metabolism and its health implications, we analyzed the scientific literature for the influence of iron fortification and supplementation on the gut microbiome and the effect of probiotics, prebiotics, and/or synbiotics in iron absorption and availability for the organism. |
| Databáze: | OpenAIRE |
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