Bowel magnetic resonance imaging of pediatric patients with oral mannitol MRI compared to endoscopy and intestinal ultrasound
| Autor: | Arne Borthne, Michael Abdelnoor, Nils-Einar Kløw, T. Reiseter, G. Perminov, J. Rugtveit |
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| Rok vydání: | 2004 |
| Předmět: |
Gadolinium DTPA
Male medicine.medical_specialty Adolescent Concordance Administration Oral Contrast Media Ileum Inflammatory bowel disease Sensitivity and Specificity Intestine Small medicine Humans Radiology Nuclear Medicine and imaging Mannitol Prospective Studies Prospective cohort study Child Neuroradiology medicine.diagnostic_test business.industry Ultrasound Reproducibility of Results Interventional radiology Magnetic resonance imaging Endoscopy Ultrasonography Doppler General Medicine Gold standard (test) medicine.disease Inflammatory Bowel Diseases Diuretics Osmotic Magnetic Resonance Imaging medicine.anatomical_structure Child Preschool Female Radiology business |
| Zdroj: | European radiology. 16(1) |
| ISSN: | 0938-7994 |
| Popis: | The purpose of this study was to assess the sensitivity, specificity, and diagnostic accuracy of magnetic resonance imaging (MRI) in pediatric patients with clinical suspicion of inflammatory bowel disease (IBD) by comparing MRI and ultrasound (US) to endoscopy, the gold standard. A median volume of 300 ml of mannitol in a 15% [corrected] watery solution were ingested by 43 children prior to examination. The 53 MRI examinations were compared with 20 endoscopies and 41 US of the terminal ileum. The outcomes were MRI quality; pathologic findings; level of adverse events; and concordance between endoscopy, MRI, and US estimated by kappa statistics. The ileum and terminal ileum were very good or excellently imaged in approximately 80% of cases. Wall thickening and enhancement were most frequent in the terminal ileum. MRI compared with endoscopy had a sensitivity of 81.8% [95% confidence interval (CI)], specificity of 100%, diagnostic accuracy of 90%, and kappa value of 0.80 (95% CI), indicating a good degree of concordance. A similar degree of concordance was achieved between US and endoscopy. In spite of the frequent adverse reactions, such as diarrhea and nausea, half of the patients were prepared to repeat the examination. The results of MRI are concordant with endoscopy and US of the terminal ileum. |
| Databáze: | OpenAIRE |
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