Heterogeneous outcome reporting in adult slow-transit constipation studies: Systematic review towards a core outcome set
| Autor: | Adriënne H Rotteveel, Stéphanie O. Breukink, Carmen D. Dirksen, Jarno Melenhorst, Merel Kimman, Stella C.M. Heemskerk |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Constipation LONG-TERM Meta Analysis and Systematic Reviews ACCELERATES COLONIC TRANSIT MEDLINE PsycINFO Outcomes Outcome (game theory) Slow-transit constipation DOUBLE-BLIND 03 medical and health sciences 0302 clinical medicine Quality of life Epidemiology Outcome Assessment Health Care medicine QUALITY EPIDEMIOLOGY Humans Slow‐transit constipation Adverse effect Defecation ANASTOMOSIS SACRAL NERVE-STIMULATION Hepatology business.industry Gastroenterology SUBTOTAL COLECTOMY Core outcome set OMERACT ELECTRICAL-STIMULATION BIOFEEDBACK 030220 oncology & carcinogenesis Physical therapy Quality of Life 030211 gastroenterology & hepatology Meta Analysis and Systematic Review Female medicine.symptom business Gastrointestinal Motility |
| Zdroj: | Journal of Gastroenterology and Hepatology |
| Popis: | Background and Aim Standardizing evaluative outcomes and their assessment facilitates comparisons between clinical studies and provides a basis for comparing direct effects of different treatment options. The aim of this study was to systematically review types of outcomes and measurement instruments used in studies regarding treatment options for slow‐transit constipation (STC) in adults. Methods In this systematic review of the literature, we searched MEDLINE, Embase, and PsycINFO from inception through February 2018, for papers assessing any STC treatment in adult patients. Outcomes were systematically extracted and categorized in domains using the conceptual framework of the Outcome Measures in Rheumatology filter 2.0. Outcome reporting was stratified by decade of publication, intervention, and study type. Results Forty‐seven studies were included in this systematic review. Fifty‐nine different types of outcomes were identified. The outcomes were structured in three core areas and 18 domains. The most commonly reported domains were defecation functions (94%), gastrointestinal transit (53%), and health‐care service use (51%). The most frequently reported outcomes were defecation frequency (83%), health‐related quality of life (43%), and adverse events and complications (43%). In 62% of the studies, no primary outcome was defined, whereas in two studies, more than one primary outcomes were selected. A wide diversity of measurement instruments was used to assess the reported outcomes. Conclusion Outcomes reported in studies on STC in adults are heterogeneous. A lack of standardization complicates comparisons between studies. Developing a core outcome set for STC in adults could contribute to standardization of outcome reporting in (future) studies. |
| Databáze: | OpenAIRE |
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