Clinical profile, management and outcomes in a cohort of elderly and highly comorbid patients with nonvalvular atrial fibrillation treated with rivaroxaban in routine practice
Autor: | Maite Villarroel Salcedo, Pilar Artero Bello, Adolfo Marquina Barcos, María Gracia Aznarez, Óscar Callen García, David Brun Guinda, Jorge Ondiviela Pérez, Elena Rivero Fernandez |
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Rok vydání: | 2018 |
Předmět: |
Male
medicine.medical_specialty Hemorrhage 030204 cardiovascular system & hematology Profile management 03 medical and health sciences 0302 clinical medicine Rivaroxaban Thromboembolism Internal medicine Atrial Fibrillation medicine Humans 030212 general & internal medicine Practice Patterns Physicians' Stroke Aged Retrospective Studies Aged 80 and over business.industry Age Factors Atrial fibrillation Retrospective cohort study Middle Aged medicine.disease Comorbidity Clinical Practice Spain Cohort Molecular Medicine Female Cardiology and Cardiovascular Medicine business Factor Xa Inhibitors medicine.drug |
Zdroj: | Future Cardiology. 14:39-45 |
ISSN: | 1744-8298 1479-6678 |
DOI: | 10.2217/fca-2018-0025 |
Popis: | Aim: To analyze clinical profile and management of patients with nonvalvular atrial fibrillation treated with rivaroxaban in clinical practice according to age and to ascertain rates of thromboembolic and bleeding events during rivaroxaban therapy. Methods: Retrospective study of nonvalvular atrial fibrillation patients that started rivaroxaban therapy between May 2013 and February 2017 in the cardiology department of two hospitals from Huesca, Spain. Results: A total of 137 patients (mean age 78.2 ± 8.9 years; CHA2DS2-VASc 3.5 ± 1.3; HAS-BLED 1.6 ± 0.7) were included. Comorbidity was common. After a mean duration of treatment of 30.5 ± 17.2 months, no strokes were reported. Rates of transient ischemic attack, major bleeding and intracranial bleeding were low. Conclusion: In this cohort of elderly and highly comorbid patients treated with rivaroxaban, rates of thromboembolic and bleeding events were low. |
Databáze: | OpenAIRE |
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