Comparison of serum thiol-disulphide homeostasis and total antioxidant-oxidant levels between exudative age-related macular degeneration patients and healthy subjects

Autor: Isil Kutluturk, Ömer Faruk Özer, Arif Koytak, Ahmet Elbay, Julide Canan Umurhan Akkan, Hakan Ozdemir, Ugur Celik
Přispěvatelé: ÖZDEMİR, MEHMET HAKAN
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Male
0301 basic medicine
medicine.medical_specialty
Antioxidant
genetic structures
Fundus Oculi
medicine.medical_treatment
Elbay A.
Ozer O. F.
AKKAN J. C. U.
Celik U.
KUTLUTURK I.
Koytak A.
OZDEMIR H.
-Comparison of serum thiol-disulphide homeostasis and total antioxidant-oxidant levels between exudative age-related macular degeneration patients and healthy subjects-
INTERNATIONAL OPHTHALMOLOGY
cilt.37
ss.1095-1101
2017
medicine.disease_cause
Antioxidants
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Homeostasis
Humans
Macula Lutea
Disulfides
Sulfhydryl Compounds
Fluorescein Angiography
Thiol disulphide homeostasis
Aged
Retrospective Studies
Aged
80 and over
chemistry.chemical_classification
business.industry
Middle Aged
Macular degeneration
Oxidants
medicine.disease
Pathophysiology
eye diseases
Surgery
Oxidative Stress
Ophthalmology
Antioxidant capacity
030104 developmental biology
Endocrinology
chemistry
Wet Macular Degeneration
030221 ophthalmology & optometry
Thiol
Female
sense organs
business
Biomarkers
Tomography
Optical Coherence
Oxidative stress
Popis: The purpose of the study was to calculate serum total oxidant status (TOS), total antioxidant status (TAS), and dynamic thiol–disulphide (T-D) homeostasis in patients with age-related macular degeneration (AMD), and compare the results with healthy individuals. Thirty-three exudative AMD patients and 33 healthy controls were included in this case–control study. Participants’ serum TAS and TOS levels were measured. In addition, total thiol (TT), native thiol (NT), and disulphide (DS) concentrations were assessed using a novel automated method of measurement. In comparison with the control group, serum TAS, TT, and NT levels were found to be significantly lower (p
Databáze: OpenAIRE
Externí odkaz: