The McGill Interactive Pediatric OncoGenetic Guidelines: An approach to identifying pediatric oncology patients most likely to benefit from a genetic evaluation
| Autor: | Stephanie Mourad, William D. Foulkes, Leora Witkowski, Hallie Coltin, Catherine Goudie, David Malkin |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty 03 medical and health sciences 0302 clinical medicine Neoplasms Pediatric oncology Medicine Humans Medical physics Genetic Predisposition to Disease Genetic Testing business.industry Cancer predisposition Hematology Guideline Mobile Applications 3. Good health 030104 developmental biology Oncology 030220 oncology & carcinogenesis Cancer genetics Pediatrics Perinatology and Child Health Physical therapy Familial Cancer business Algorithms |
| Zdroj: | Pediatric bloodcancer. 64(8) |
| ISSN: | 1545-5017 |
| Popis: | Identifying cancer predisposition syndromes in children with tumors is crucial, yet few clinical guidelines exist to identify children at high risk of having germline mutations. The McGill Interactive Pediatric OncoGenetic Guidelines project aims to create a validated pediatric guideline in the form of a smartphone/tablet application using algorithms to process clinical data and help determine whether to refer a child for genetic assessment. This paper discusses the initial stages of the project, focusing on its overall structure, the methodology underpinning the algorithms, and the upcoming algorithm validation process. |
| Databáze: | OpenAIRE |
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