Poliovirus: new insights from an old paradigm
Autor: | Michelle W. Wien, Marie Chow, James M. Hogle |
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Rok vydání: | 1996 |
Předmět: |
Cell entry
Models Molecular Future studies Molecular Structure Poliovirus viruses Virus Physiology Membrane Proteins Computational biology Biology medicine.disease_cause Virology Virus Viral Assembly Structure-Activity Relationship Viral genetics Structural Biology medicine RNA Viral Receptors Virus Molecular Biology |
Zdroj: | Structure (London, England : 1993). 4(7) |
ISSN: | 0969-2126 |
Popis: | A combination of structural and genetic studies of poliovirus suggests that the final stages of viral assembly lock the virus in a metastable structure primed to undergo the receptor-catalyzed conformational changes required for cell entry. Future studies promise to provide detailed insights into the conformational dynamics of the virion during its life cycle. |
Databáze: | OpenAIRE |
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