Sex differences in the relationship of sleep-disordered breathing and asthma control among children with severe asthma
| Autor: | Jonathan M. Gaffin, Gabriella C. Sierra, Natalie P. Stamatiadis, Adam Hammond, Umakanth Katwa, Christine Thayer, Tregony Simoneau, Sachin N. Baxi, Lauren M. Giancola, Kimberly F. Greco, Carter R. Petty, Sigfus Gunnlaugsson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male Pediatrics medicine.medical_specialty Severe asthma macromolecular substances Article 03 medical and health sciences 0302 clinical medicine Sleep Apnea Syndromes immune system diseases 030225 pediatrics Asthma control Surveys and Questionnaires medicine Immunology and Allergy Humans Child Pediatric asthma Asthma Sex Characteristics business.industry medicine.disease respiratory tract diseases Obstructive sleep apnea 030228 respiratory system Pediatrics Perinatology and Child Health Sleep disordered breathing Breathing Female business Sleep |
| Zdroj: | J Asthma |
| Popis: | OBJECTIVE: Children with severe asthma are underrepresented in studies of the relationship of sleep-disordered breathing (SDB) and asthma and little is known about sex differences of these relationships. We sought to determine the relationship of SDB with asthma control and lung function among boys and girls within a pediatric severe asthma cohort. METHODS: Patients attending clinic visits at the Boston Children’s Hospital Pediatric Severe Asthma Program completed the Pediatric Sleep Questionnaire (PSQ), Asthma Control Test (ACT) and Spirometry. The prevalence of SDB was defined as a PSQ score >0.33. We analyzed the association between PSQ score and both ACT score and spirometry values in mixed effect models, testing interactions for age and sex. RESULTS: Among 37 subjects, mean age was 11.8 years (4.4) and 23 (62.2%) were male, the prevalence of SDB was 43.2% (16/37). Including all 80 observations, there was a moderate negative correlation between PSQ and ACT scores (r=−0.46, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|