Pre-operative nutritional support in children with end-stage liver disease accepted for liver transplantation: An approach to management
| Autor: | M. K. Patrick, J. A. Wilcox, T. H. Ong, S. E. Chin, Russell W. Strong, Stephen V. Lynch, Geoffrey J. Cleghorn, Ross W. Shepherd |
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| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Nutritional Status Liver transplantation Chronic liver disease Gastroenterology Enteral administration Liver disease Enteral Nutrition Biliary Atresia Biliary atresia Internal medicine Preoperative Care medicine Humans Food Formulated Hepatology business.industry Nutrition Disorders Infant medicine.disease Liver Transplantation Malnutrition Parenteral nutrition Female Energy Intake business Amino Acids Branched-Chain |
| Zdroj: | Journal of Gastroenterology and Hepatology. 5:566-572 |
| ISSN: | 1440-1746 0815-9319 |
| Popis: | Pre-operative nutritional support was studied in 28 children with end-stage liver disease awaiting orthotopic liver transplantation. Nasogastric supplemental administration of a standard semi-elemental enteral nutritional formula was compared with a similar formula enriched with branched chain amino acids, and with a group receiving oral nutrition only. The duration of treatment in all groups was similar (mean 90 days). Energy intakes in the supplemented groups were 120-150% of recommended daily intakes (RDI), whereas ad libitum intakes in the oral group ranged 58-100% RDI. A significant improvement in mean Z-score for body weight (denoting catch-up) was noted only in those children who received nasogastric supplements enriched with branched-chain amino acids. The standard enterally-fed group maintained their body weight and Z-scores did not change significantly. In contrast, body weight Z-scores in those fed orally declined significantly. Nutritional supportive therapy of malnourished children with end-stage liver disease can minimize or improve nutritional status in children awaiting liver transplantation. The use of nutritional formulae rich in branched-chain amino acids may have nutritional advantages in children with chronic liver disease which require further study and evaluation. |
| Databáze: | OpenAIRE |
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