| Autor: |
Judd W. Moul, Renee M. Mooneyhan, David G. McLeod, Roger R. Connelly, Wei Zhang, Isabell A. Sesterhenn, F. K. Mostofi |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
The Journal of Urology. :394-397 |
| ISSN: |
0022-5347 |
| DOI: |
10.1097/00005392-199908000-00028 |
| Popis: |
Purpose: Black men with and without prostate cancer in general have higher prostate specific antigen (PSA) before screening and treatment than other racial groups. A preliminary study suggested that higher PSA levels may be primarily due to greater tumor burden. We compared PSA and 3-dimensional (D) tumor volume in a consecutive cohort of black and white radical prostatectomy patients in an equal access military health care setting to determine racial differences in these parameters.Materials and Methods: Prospective data collection, 2.25 mm. step section whole mount specimen processing and 3-D tumor volume assessment were performed in 226 patients with clinical stage T1-T3 prostate cancer undergoing radical prostatectomy at our center between April 1993 and March 1997. Of the patients 25 were excluded from further analysis because of neoadjuvant hormone treatment, T3 disease or Asian race. A total of 155 white and 46 black patients were compared.Results: There was no significant racial difference... |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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