New indicators for systematic assessment of aortic morphology: a narrative review
| Autor: | Weiguo Fu, Mao Le, Jingyang Luan, Ziqing Zhu, Ting Zhu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Aorta business.industry Disease Review Article 030204 cardiovascular system & hematology medicine.disease Thoracic aortic aneurysm 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Single indicator medicine.artery Assessment methods medicine Predictive power cardiovascular system Narrative review Adverse effect Intensive care medicine business |
| Zdroj: | J Thorac Dis |
| ISSN: | 2072-1439 |
| Popis: | In order to prevent the occurrence of aortic adverse events in ascending thoracic aortic aneurysm patients, preventive surgery is the sole option in case of large aneurysm. Identifying high-risk patients timely and accurately requires effective predictive indicators of aortic adverse events and accurate risk stratification thresholds. Absolute diameter measured after a single imaging examination, which has been used as the predictive indicator for decades, has been proved to be ineffective for risk stratification in moderately dilated aorta. Previously, new indicators combining absolute diameters with personalized parameters have been reported to show better predictive power of aortic adverse events than absolute diameters by correcting the effect of these parameters on the diameters. Meanwhile, combining three-dimensional parameters to formulate risk stratification thresholds not only may characterize the aortic risk morphology more precisely, but also predict aortic adverse events more accurately. These new indicators may provide more systematic assessment methods of patients' risk, formulate more personalized intervention strategies for ascending thoracic aortic aneurysm patients, and also provide a basis for researchers to develop more accurate and effective risk thresholds. We also highlight that the algorithm obtained by combining multiple indicators may be a better choice compared with single indicator, but this still requires the support of more evidence. Due to the particularity of syndromic aortic disease, whether these new indicators can be used for its risk stratification is still uncertain. Therefore, the scope of this manuscript does not include this kind of disease. |
| Databáze: | OpenAIRE |
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