Ultrathin Functional Polymer Modified Graphene for Enhanced Enzymatic Electrochemical Sensing
| Autor: | Hina Y. Abbasi, Zari Tehrani, Yufei Liu, Muhammad Munem Ali, Owen J. Guy, Rhiannan Forsyth, Ryan Bigham, Anitha Devadoss |
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| Jazyk: | angličtina |
| Předmět: |
Materials science
Immobilized enzyme Polymers Surface Properties lcsh:Biotechnology Clinical Biochemistry Biosensing Techniques 02 engineering and technology Chemical vapor deposition 010402 general chemistry Electrochemistry 01 natural sciences Article law.invention chemistry.chemical_compound bio electrochemistry law lcsh:TP248.13-248.65 Electrodes Horseradish Peroxidase enzyme immobilization chemistry.chemical_classification glucose biosensor Graphene Biomolecule biofunctionalization electropolymerization electrochemical sensing Electrochemical Techniques Hydrogen Peroxide General Medicine Polymer Enzymes Immobilized 021001 nanoscience & nanotechnology 0104 chemical sciences Glucose Monomer chemistry Chemical engineering functional polymers Graphite Functional polymers 0210 nano-technology |
| Zdroj: | Biosensors Volume 9 Issue 1 Biosensors, Vol 9, Iss 1, p 16 (2019) |
| ISSN: | 2079-6374 |
| DOI: | 10.3390/bios9010016 |
| Popis: | Grafting thin polymer layers on graphene enables coupling target biomolecules to graphene surfaces, especially through amide and aldehyde linkages with carboxylic acid and primary amine derivatives, respectively. However, functionalizing monolayer graphene with thin polymer layers without affecting their exceptional electrical properties remains challenging. Herein, we demonstrate the controlled modification of chemical vapor deposition (CVD) grown single layer graphene with ultrathin polymer 1,5-diaminonaphthalene (DAN) layers using the electropolymerization technique. It is observed that the controlled electropolymerization of DAN monomer offers continuous polymer layers with thickness ranging between 5–25 nm. The surface characteristics of pure and polymer modified graphene was examined. As anticipated, the number of surface amine groups increases with increases in the layer thickness. The effects of polymer thickness on the electron transfer rates were studied in detail and a simple route for the estimation of surface coverage of amine groups was demonstrated using the electrochemical analysis. The implications of grafting ultrathin polymer layers on graphene towards horseradish peroxidase (HRP) enzyme immobilization and enzymatic electrochemical sensing of H2O2 were discussed elaborately. |
| Databáze: | OpenAIRE |
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