Lewis Acid-Catalyzed Nucleophilic Substitutions of Propargylic and Allylic Silyl Ethers with Enol Silyl Ethers

Autor:	Toshiaki Aikawa, Teruhiko Ishikawa, Yumiko Mori, Seiki Saito
Rok vydání:	2002
Předmět:	Allylic rearrangement Enyne Silylation Chemistry Organic Chemistry Carbocation Biochemistry Medicinal chemistry Enol chemistry.chemical_compound Nucleophile Propargyl Lewis acids and bases Physical and Theoretical Chemistry
Zdroj:	Organic Letters. 5:51-54
ISSN:	1523-7052 1523-7060
DOI:	10.1021/ol0271537
Popis:	Nucleophilic reactions of various enol silyl ethers with carbocation species generated from propargyl silyl ethers by the action of a Lewis acid have been developed. The present method is highly useful for the introduction of allenic or enyne functionalities into the alpha-position of substituted ketones. [reaction--see text]
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c3f2bb9f923efa91c8fbe1110616e8 https://doi.org/10.1021/ol0271537 Zobrazit plný text záznamu