Acupuncture for Treatment of Erectile Dysfunction: A Systematic Review and Meta-Analysis
| Autor: | Xin Lin Li, Emma Wong, Li Yan Jia, Hui Juan Cao, Xiao Ying Yang, Suzanne J Grant, Guoyan Yang, Bao Yong Lai, Jianping Liu, Yu Tong Fei |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Aging
medicine.medical_specialty Urology 030232 urology & nephrology lcsh:Medicine lcsh:RC870-923 law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine Acupuncture Medicine Psychogenic disease Pharmacology (medical) Erectile dysfunction 030219 obstetrics & reproductive medicine business.industry Health Policy lcsh:R Public Health Environmental and Occupational Health medicine.disease lcsh:Diseases of the genitourinary system. Urology Tadalafil 3. Good health Psychiatry and Mental health Meta-analysis Reproductive Medicine Relative risk Adjunctive treatment Systematic review Original Article business medicine.drug |
| Zdroj: | The World Journal of Men's Health, Vol 37, Iss 3, Pp 322-338 (2019) The World Journal of Men's Health |
| ISSN: | 2287-4690 2287-4208 |
| Popis: | Purpose To assess the effectiveness and safety of acupuncture for erectile dysfunction (ED). Materials and methods We searched six major English and Chinese databases included randomized controlled trials (RCTs) testing acupuncture alone or in combination for ED. Dichotomous data were presented as risk ratio (RR) and continuous data were presented as mean difference (MD) both with 95% confidence interval (CI). The Revman (v.5.3) was used for data analyses. Quality of evidence across studies was assessed by the online GRADEpro tool. Results We identified 22 RCTs, fourteen of them involving psychogenic ED. Most of the included RCTs had high or unclear risk of bias. There was no difference between electro-acupuncture and sham acupuncture with electrical stimulation on the rate of satisfaction and self-assessment (RR, 1.50; 95% CI, 0.71-3.16; 1 trial). Acupuncture combined with tadalafil appeared to have better effect on increasing cure rate (RR, 1.31; 95% CI, 1.00-1.71; 2 trials), and International Index of Erectile Function-5 scores (MD, 5.38; 95% CI, 4.46-6.29; 2 trials). When acupuncture plus herbal medicine compared with herbal medicine alone, the combination therapy showed significant better improvement in erectile function (RR, 1.68; 95% CI, 1.31-2.15; 7 trials). Only two trials reported facial red and dizziness cases, and needle sticking and pruritus cases in acupuncture group. Conclusions Low quality evidence shows beneficial effect of acupuncture as adjunctive treatment for people mainly with psychogenic ED. Safety of acupuncture was insufficiently reported. The findings should be confirmed in large, rigorously designed and well-reported trials. |
| Databáze: | OpenAIRE |
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