Sarcoidosis of the CNS: comparison of unenhanced and enhanced MR images
| Autor: | J L Sherman, B J Stern |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Gadolinium DTPA Male Pituitary gland medicine.medical_specialty Pathology Sarcoidosis Contrast Media Optic chiasm Gadolinium Meglumine Parenchyma Organometallic Compounds medicine Humans Comparative Study Radiology Nuclear Medicine and imaging Retrospective Studies Brain Diseases medicine.diagnostic_test business.industry Leptomeninges Magnetic resonance imaging General Medicine Middle Aged Pentetic Acid Image Enhancement medicine.disease Magnetic Resonance Imaging Drug Combinations medicine.anatomical_structure Female Radiology Ependyma business medicine.drug |
| Zdroj: | AJNR Am J Neuroradiol |
| ISSN: | 1546-3141 0361-803X |
| DOI: | 10.2214/ajr.155.6.2122683 |
| Popis: | Sarcoidosis involving the CNS has a predilection for the leptomeninges, although parenchymal involvement occurs. We retrospectively evaluated the appearance of CNS sarcoidosis on unenhanced and enhanced MR images. MR studies were abnormal in 17 of 20 patients with CNS sarcoidosis. In all 17 patients, meningeal disease was detected on the gadopentetate-dimeglumine-enhanced T1-weighted images; the disease was detected on unenhanced images in three patients. Well-defined leptomeningeal patterns of enhancement were present in 15 patients. Other areas of involvement were the dura; brain parenchyma including hypothalamus, periventricular white matter, and ventricular ependyma; optic chiasm; and pituitary gland. Gadopentetate dimeglumine optimally evaluates meningeal disease and highlights the importance of the leptomeninges and Virchow-Robin spaces in the pathogenesis of CNS sarcoidosis. Enhanced MR is the preferred imaging technique for the evaluation of CNS sarcoidosis. |
| Databáze: | OpenAIRE |
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