In Vitro Activity of a Hypochlorous Acid-Generating Electrochemical Bandage against Yeast Biofilms

Autor:	Joseph Kletzer, Yash S. Raval, Abdelrhman Mohamed, Jayawant N. Mandrekar, Kerryl E. Greenwood-Quaintance, Haluk Beyenal, Robin Patel
Rok vydání:	2023
Předmět:	Pharmacology Infectious Diseases Experimental Therapeutics Pharmacology (medical)
Zdroj:	Antimicrob Agents Chemother
ISSN:	1098-6596 0066-4804
Popis:	The antibiofilm activity of a hypochlorous acid (HOCl)-producing electrochemical bandage (e-bandage) was assessed against 14 yeast isolates in vitro. The evaluated e-bandage was polarized at +1.5 V(Ag/AgCl) to allow continuous production of HOCl. Time-dependent decreases in the biofilm CFU counts were observed for all isolates with e-bandage treatment. The results suggest that the described HOCl-producing e-bandage could serve as a potential alternative to traditional antifungal wound biofilm treatments.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b953e44f9fa089b3e870bac9440c80 https://doi.org/10.1128/aac.01166-22 Zobrazit plný text záznamu