Scientific and ethical issues of preimplantation diagnosis
Autor: | Anne-Marie Nagy, N. Ruibal, F. A. Lints, X. De Man |
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Rok vydání: | 1998 |
Předmět: |
Male
Gynecology medicine.medical_specialty Ethical issues business.industry Genetic Diseases Inborn PID controller Prenatal diagnosis General Medicine First birth Risk analysis (engineering) Pregnancy Prenatal Diagnosis SAFER Humans Medicine Ethics Medical Female business Genetic diagnosis Ovum implantation Preimplantation Diagnosis Selection (genetic algorithm) |
Zdroj: | Annals of Medicine. 30:1-6 |
ISSN: | 1365-2060 0785-3890 |
DOI: | 10.3109/07853899808999379 |
Popis: | Preimplantation diagnosis (PID) offers couples at high risk of having offspring affected with a genetic disorder the possibility of an early prenatal diagnosis. For many couples this approach will give the opportunity to avoid a selective termination of affected pregnancies. Substantial advances were made in PID since the report, in 1990, of the first birth obtained after PID. Yet, many technical hazards have to be solved for PID to become a standard clinical tool. The very close correlation existing between the forthcoming developments in the fields of PID and human genome mapping will improve the reliability and efficiency of genetic diagnosis. In the near future, the procedure may also become easier and safer. As a consequence, the indications for PID could be extended to other genetic defects, such as multifactorial diseases. They could also be extended to cases with no medical background, such as social gender selection or behavioural traits. In this perspective, it is now time for both the medical and scientific communities to identify the ethical issues related to these potential new indications. |
Databáze: | OpenAIRE |
Externí odkaz: |
Abstrakt: | Preimplantation diagnosis (PID) offers couples at high risk of having offspring affected with a genetic disorder the possibility of an early prenatal diagnosis. For many couples this approach will give the opportunity to avoid a selective termination of affected pregnancies. Substantial advances were made in PID since the report, in 1990, of the first birth obtained after PID. Yet, many technical hazards have to be solved for PID to become a standard clinical tool. The very close correlation existing between the forthcoming developments in the fields of PID and human genome mapping will improve the reliability and efficiency of genetic diagnosis. In the near future, the procedure may also become easier and safer. As a consequence, the indications for PID could be extended to other genetic defects, such as multifactorial diseases. They could also be extended to cases with no medical background, such as social gender selection or behavioural traits. In this perspective, it is now time for both the medical and scientific communities to identify the ethical issues related to these potential new indications. |
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ISSN: | 13652060 07853890 |
DOI: | 10.3109/07853899808999379 |