Chronic lower extremity wound infection due to Kerstersia gyiorum in a patient with Buerger’s disease: a case report

Autor: İpek Mumcuoğlu, Irmak Baran, Neriman Aksu, Arife Polat Düzgün
Přispěvatelé: Mikrobiyoloji
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0301 basic medicine
Chronic wound
Male
medicine.medical_specialty
Pathology
030106 microbiology
Proteus vulgaris
Case Report
lcsh:Infectious and parasitic diseases
law.invention
Foot Diseases
03 medical and health sciences
Medical microbiology
law
RNA
Ribosomal
16S
medicine
MALDI-TOF MS
Humans
lcsh:RC109-216
16S rRNA gene sequencing
Buerger's disease
biology
business.industry
Thromboangiitis Obliterans
Chronic wound infection
Buerger’s Disease
6S rRNA gene sequencing
Middle Aged
biology.organism_classification
medicine.disease
Tıp
Anti-Bacterial Agents
Chronic infection
Infectious Diseases
Gram staining
Spectrometry
Mass
Matrix-Assisted Laser Desorption-Ionization
Kerstersia gyiorum
Chronic Disease
Wound Infection
medicine.symptom
business
Morganella morganii
Gram-Negative Bacterial Infections
Alcaligenaceae
Zdroj: BMC Infectious Diseases
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-8 (2017)
ISSN: 1471-2334
Popis: Background Kerstersia gyiorum is an extremely rare pathogen of human infection. It can cause chronic infection in patients with underlying conditions. It can easily be misdiagnosed if proper diagnostic methods are not used. Case presentation A 47-year-old male patient with a history of Buerger’s Disease for 28 years presented to our hospital with an infected chronic wound on foot. The wound was debrided, and the specimen was sent to Microbiology laboratory. Gram staining of the specimen showed abundant polymorphonuclear leukocytes and gram-negative bacilli. Four types of colonies were isolated on blood agar. These were identified as Kerstersia gyiorum, Proteus vulgaris, Enterobacter cloacae, Morganella morganii by Maldi Biotyper (Bruker Daltonics, Germany). The identification of K. gyiorum was confirmed by 16S ribosomal RNA gene sequencing. The patient was successfully recovered with antimicrobial therapy, surgical debridement, and skin grafting. Conclusions This is the first case of wound infection due to K. gyiorum in a patient with Buerger’s Disease. We made a brief review of K. gyiorum cases up to date. Also, this case is presented to draw attention to the use of new and advanced methods like MALDI-TOF MS and 16S rRNA gene sequencing for identification of rarely isolated species from clinical specimens of patients with chronic infections and with chronic underlying conditions.
Databáze: OpenAIRE
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