The Modified Bose Method for the Endovascular Treatment of Intracranial Atherosclerotic Arterial Stenoses Using the Enterprise Stent
| Autor: | Elisabeth Schmid, Jan Peters, Wolfgang Sperber, Hans Henkes, Ludwig Niehaus, Guy Arnold, Christoph Klötzsch, A. Lindner, Thomas Güthe, Hansjörg Bäzner, Zsolt Vajda |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Vertebral artery Medizin Posterior cerebral artery Restenosis medicine.artery Angioplasty Basilar artery Humans Medicine Aged Aged 80 and over business.industry Angiography Digital Subtraction Stent Middle Aged Intracranial Arteriosclerosis medicine.disease Surgery Stenosis Treatment Outcome ROC Curve Female Stents Neurology (clinical) Radiology Internal carotid artery business Angioplasty Balloon Carotid Artery Internal Follow-Up Studies |
| Popis: | Background Balloon dilatation and deployment of a self-expanding stent is a safe treatment for intracranial atherosclerotic stenoses. The significant recurrence rate might be related to the high radial force of the Wingspan stent. Objective To evaluate the procedural safety and stenosis recurrence rate by the use of a stent with reduced radial force (Enterprise). Methods Two hundred nine atherosclerotic stenoses (189 patients) were treated (median age, 68 years; 132 male) in a single center. Lesion locations included internal carotid artery (n = 27), middle cerebral artery (n = 62), vertebral artery (n = 64), basilar artery (n = 55), and posterior cerebral artery (n = 1). Pre- and postmedication included acetylsalicylic acid and Clopidogrel for at least 12 months. Preprocedural and follow-up examinations included magnetic resonance imaging (MRI), neurological assessment, and digital subtraction angiography (6, 12, 26, and 52 weeks). Data registry included age, sex, normal vessel diameter, degree of stenosis, residual stenosis after stent, minimal in-stent diameter, and occurrence of ischemic symptoms during follow-up. Results Median pre- and postprocedural stenosis rate was 65.4 ± 1% vs 25.1 ± 1%. Technical success rate was 100%. Major procedural complications occurred in 16 patients (8.1%). Combined neurological morbidity and mortality rate at 30 days was 2 patients (0.9%). In 174 stenoses (83%) angiographic follow-up was obtained (mean, 10.2 months). A restenosis (>50%) was observed in 43 (24.7%) cases after 4.2 months (mean) with 4 (9.3%) symptomatic lesions. Incidence of recurrent ischemia related to the stented artery was 2.2% during 10.2 months of mean follow-up. Conclusion Undersized balloon angioplasty and deployment of an Enterprise stent is safe and effective for intracranial stenoses. Follow-up results were equal to or better than those reported for bare-metal balloon-expandable or self-expanding stents and yielded excellent protection from recurrent ischemia. |
| Databáze: | OpenAIRE |
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