The Evolution of Human Probiotics: Challenges and Prospects
| Autor: | Yuri M. Poluektov, O.S. Shifrin, Allan G Beniashvilli, Elizaveta A Trush, Elena Poluektova, Vladimir Ivashkin |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty 030106 microbiology Physical activity Capsules Optimal composition Microbiology law.invention Helicobacter Infections 03 medical and health sciences Probiotic Human health Bacteriocins law Medicine Humans Medical prescription Intensive care medicine Molecular Biology Clinical Trials as Topic Microbial Viability business.industry Probiotics Microbial composition Plankton Unbalanced diet Gastrointestinal Microbiome Saccharomyces boulardii Lactobacillus 030104 developmental biology Biofilms Clostridium Infections Molecular Medicine Colitis Ulcerative Bifidobacterium business |
| Zdroj: | Probiotics and antimicrobial proteins. 12(4) |
| ISSN: | 1867-1314 |
| Popis: | In recent years, the intestinal microbiota has been found to greatly influence a number of biological processes important for human health and longevity. Microbial composition changes easily in response to external factors, such as an unbalanced diet, lack of physical activity, and smoking. Probiotics are a key factor in maintaining the optimal composition of the intestinal microbiota. However, a number of important questions related to probiotics, such as indication for prescription, comparative efficacy of monostrain and multistrain probiotics, methods of delivery, and shelf life, remain unresolved. The aim of this review is to highlight existing issues regarding probiotic production and their prescription. The review presents the most recent findings regarding advantages and efficacy of monostrain and multistrain probiotics, preservation of probiotic strains in capsules and microcapsules, production of probiotics in the form of biofilms for improved efficacy and survival, and results of clinical studies evaluating the benefits of probiotics against different pathologies. We believe that this work will be of interest to physicians and researchers alike and will promote the development of new probiotics and ensuing regimens aimed at the treatment of various diseases. |
| Databáze: | OpenAIRE |
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