Preparation of a New Polymeric Deep Eutectic Solvent and Its Application in Vortex-Assisted Liquid-Liquid Microextraction of Parabens in Foods, Cosmetics and Pharmaceutical Products
| Autor: | Yunxin Cao, Enrui Dai, Ying Gao, Lin Yuan, Dandan Ge |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Detection limit
Materials science Chromatography high performance liquid chromatography media_common.quotation_subject Extraction (chemistry) deep eutectic solvent General Chemistry Polyethylene glycol Cosmetics High-performance liquid chromatography Deep eutectic solvent vortex-assisted dispersive liquid-liquid microextraction parabens Solvent chemistry.chemical_compound chemistry Eutectic system media_common |
| Zdroj: | Journal of the Brazilian Chemical Society, Volume: 31, Issue: 10, Pages: 2120-2128, Published: 09 OCT 2020 Journal of the Brazilian Chemical Society v.31 n.10 2020 Journal of the Brazilian Chemical Society Sociedade Brasileira de Química (SBQ) instacron:SBQ |
| Popis: | A vortex-assisted liquid-liquid microextraction method combined with high performance liquid chromatography-diode array detector has been developed for the determination of parabens in foods, cosmetics and pharmaceutical products. In this work, polymeric deep eutectic solvents composed of DL-menthol and polyethylene glycol with three different light grades were prepared successfully for the first time and used as extraction solvents. The influencing parameters on the extraction efficiency including type of extraction solvent, salt addition, composition of deep eutectic solvent, volume of extraction solvent, extraction time and solution pH were evaluated. Under the optimized conditions, using DL-menthol and polyethylene glycol 400 at a molar ratio of 1:1 as the extraction solvent, the method exhibited good linearity with linear coefficients greater than 0.9995. Limits of detection and limits of quantification were in the range of 0.3-2 ng mL-1 and 1-5 ng mL-1, respectively. The proposed method was successfully applied to determine four parabens in seven commercial products. The proposed method is simple, green and efficient, and could be applied to determine parabens in complex matrices. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|