High b value q-space-analyzed diffusion MRI in vascular dementia: A preliminary study
Autor: | Moshe Graif, Amos D. Korczyn, I.I Reider-Groswasser, Dafna Ben-Bashat, Ruth Verchovsky, Yaniv Assaf, Ariela Gigi, Yoram Cohen, Talma Hendler, Orna Mayzel-Oreg, M. Mordohovitch |
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Rok vydání: | 2002 |
Předmět: |
Male
medicine.medical_specialty White matter Neuroimaging Alzheimer Disease Image Processing Computer-Assisted medicine Humans Dementia cardiovascular diseases Vascular dementia Aged Probability medicine.diagnostic_test business.industry Dementia Vascular Leukoaraiosis Brain Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging Hyperintensity medicine.anatomical_structure Neurology Female Neurology (clinical) Radiology Nuclear medicine business Diffusion MRI |
Zdroj: | Journal of the Neurological Sciences. :235-239 |
ISSN: | 0022-510X |
Popis: | High b value diffusion weighted magnetic resonance imaging (high-b DWI) was used to characterize white matter changes in the brain of patients with vascular dementia (VaD). Hyperintense white matter areas detected by T2-weighted magnetic resonance imaging (MRI) represent lesions, also termed leukoaraiosis that are very common in VaD as well as in other types of dementia. Therefore, the role of white matter changes in the cognitive and memory decline that occurs in VaD patients is still under debate. High-b DWI, analyzed using the q-space approach, is a more sensitive MRI method for detection of white matter changes. High-b DWI revealed massive white matter loss in VaD patients that surpassed the boundaries of T2 hyperintensities. This technique, therefore, might serve as a better indication for the extensive nerve fiber loss in the white matter that is caused by vascular disease. |
Databáze: | OpenAIRE |
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