Methicillin-resistant Staphylococcus aureus in the western region of Saudi Arabia: prevalence and antibiotic susceptibility pattern
| Autor: | Nagwa El Amin, Hani S. Faidah |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Methicillin-Resistant Staphylococcus aureus Staphylococcus aureus medicine.medical_specialty Adolescent medicine.drug_class Antibiotics lcsh:Medicine Microbial Sensitivity Tests medicine.disease_cause Young Adult Internal medicine Prevalence medicine Humans Intensive care medicine Retrospective Studies Susceptibility pattern business.industry lcsh:R General Medicine Middle Aged Staphylococcal Infections biochemical phenomena metabolism and nutrition bacterial infections and mycoses Methicillin-resistant Staphylococcus aureus Female business |
| Zdroj: | Annals of Saudi Medicine, Vol 32, Iss 5, Pp 513-516 (2012) |
| ISSN: | 0975-4466 0256-4947 |
| Popis: | BACKGROUND AND OBJECTIVES: Methicillin-resistant Staphylococcus aureus (MRSA) emerged in 1960 and was a problem confined largely to the healthcare setting, or hospital-associated MRSA (HA-MRSA). In the 1990s, community-associated MRSA (CA-MRSA) infections appeared. In Saudi Arabia, the prevalence of MRSA has increased in the past ten years and severe community-acquired infection has been reported. Our objective was to investigate the prevalence of MRSA and their antibiotic susceptibilities in the western region of Saudi Arabia. DESIGN AND SETTING: A retrospective review of the medical records of 186 S aureus infected patients diagnosed from November 2009 through October 2010. METHODS: S aureus was Identified based on Gram stain, catalase and coagulase tests. Susceptibility testing was performed using antibiotic discs and the VITEK 2 system. RESULTS: MRSA was isolated in 39.5% of the specimens. The isolates were commonly associated with wound, skin, and soft tissue infections (87.3%). The prevalence of MRSA was highest among patients who were 56 years old or older (52.2%). CA-MRSA infections represented 31.5% of community S aureus infections, while HA-MRSA accounted 52.6% of hospital S aureus (P=.0029). All MRSA isolates in our study were susceptible to vancomycin, linozolid and teicoplanin. However, multi-resistance was observed in 29.1% of the isolates and was significantly higher among HA-MRSA (P=.03). CONCLUSIONS: The prevalence of MRSA was 39.5%, and infection was commonly associated with wound, skin, and soft tissue infections. MRSA was more prevalent in hospitals and among older patients. All MRSA susceptible to vancomycin, linozolid and teicoplanin. |
| Databáze: | OpenAIRE |
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