Multiple whole genome alignments and novel biomedical applications at the VISTA portal
| Autor: | Michael Brudno, Alexander Poliakov, Igor Ratnere, Simon Minovitsky, Inna Dubchak |
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| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
ComputerSystemsOrganization_COMPUTERSYSTEMIMPLEMENTATION
Molecular Sequence Data Genomics Biology Genome Polymorphism Single Nucleotide 03 medical and health sciences Annotation 0302 clinical medicine Dogs Sequence Homology Nucleic Acid Genetics Animals Humans Base sequence 030304 developmental biology Comparative genomics 0303 health sciences Internet Information retrieval Base Sequence Genome Human Life Sciences Computational Biology Articles Sequence Analysis DNA Visualization VISTA comparative genomics DNA sequence Human genome Chickens Sequence Alignment 030217 neurology & neurosurgery Software |
| Zdroj: | Nucleic Acids Research Brudno, Michael; Poliakov, Alexander; Minovitsky, Simon; Ratnere, Igor; & Dubchak, Inna. (2008). Multiple Whole Genome Alignments and Novel Biomedical Applications at the VISTA Portal. Lawrence Berkeley National Laboratory. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/5326x08w |
| ISSN: | 1362-4962 0305-1048 |
| Popis: | The VISTA portal for comparative genomics is designed to give biomedical scientists a unified set of tools to lead them from the raw DNA sequences through the alignment and annotation to the visualization of the results. The VISTA portal also hosts alignments of a number of genomes computed by our group, allowing users to study regions of their interest without having to manually download the individual sequences. Here we describe various algorithmic and functional improvements implemented in the VISTA portal over the last two years. The VISTA Portal is accessible at http://genome.lbl.gov/vista. |
| Databáze: | OpenAIRE |
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