SAP and Lessons Learned from a Primary Immunodeficiency

Autor:	J, Sayos, C, Wu, M, Morra, N, Wang, X, Zhang, D, Allen, S, van Schaik, L, Notarangelo, R, Geha, M G, Roncarolo, H, Oettgen, J E, De Vries, G, Aversa, C, Terhorst
Rok vydání:	2017
Předmět:	0301 basic medicine Adult Male T-Lymphocytes Immunology Biology Lymphocyte Activation Article 03 medical and health sciences Jurkat Cells Mice Young Adult Signaling Lymphocytic Activation Molecule Family Member 1 Cell surface receptor Allergy and Immunology medicine Immunology and Allergy Animals Humans Signaling Lymphocytic Activation Molecule Associated Protein Cloning Molecular Gene SIGNALING LYMPHOCYTE ACTIVATION MOLECULE Cloning Immunologic Deficiency Syndromes Signal transducing adaptor protein History 20th Century medicine.disease Lymphoproliferative Disorders Cell biology Mice Inbred C57BL 030104 developmental biology Mutation Primary immunodeficiency Sequence Alignment Intracellular
Zdroj:	Journal of immunology (Baltimore, Md. : 1950). 199(5)
ISSN:	1550-6606
Popis:	Approximately 19 years ago, Terhorst and colleagues ([1][1]) reported the cloning of the gene encoding a small adaptor protein, signaling lymphocyte activation molecule (SLAM)-associated protein (SAP), named by virtue of its binding to the intracellular tail of the cell surface receptor SLAM.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888cb408fb2dd0051362ecfbde4dbe2e https://pubmed.ncbi.nlm.nih.gov/28827385 Zobrazit plný text záznamu