| Autor: |
Nam Sik Chung, Byung Hee Oh, Myeng Chan Cho, Dong Soo Kim, Young Dae Kim, Young Moo Ro, Jin Won Jeong, Kyung Ho Youn, Wang Seong Ryu, Won Ho Kim, Jong Chun Park, Gae Hoon Kim, Dong Gu Shin, Se Joong Rim, Sung Ha Park, Dong Ju Choi, Soo Yeun Choi, Moo Yong Rhee, Chang Gyu Park, Jang Ho Bae, Shung Chull Chae, Kyu Hyung Ryu, Sang Hong Baek, Ho Joong Youn, Kee Sik Kim, Jeong Bae Park |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Artery Research, Vol 3, Iss 3 (2009) |
| ISSN: |
1876-4401 |
| DOI: |
10.1016/j.artres.2009.06.032 |
| Popis: |
Background: Aging exerts a number of deleterious changes in the cardiovascular system, and, in particular, on the large arteries. Previous studies have suggested that augmentation index (Aix) and aortic pulse wave velocity (aPWV) increase linearly with age, yet epidemiological data concerning arterial stiffness suggest that large artery stiffening predominantly occurs later in life. Therefore, the aim of the study was to test the hypothesis; 1) age-related changes in AIx are more prominent in younger individuals, whereas changes in aortic stiffness per se are more marked in older individuals, 2) whether these changes are similar between Caucasians and Koreans. Methods: 1,188 subjects aged 17 to 87 years (mean age of 45.5 years and female 52%) were included and all were apparently healthy and free of any medication for hypertension, diabetes and dyslipidemia. Aix and aPWV were measured by pp-1000 and Gaon 21 (both Hanbyul Medtech, Korea). Results: Women showed significantly higher central Aix (15.4 vs. 22.5 of men, p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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