Assessment of left ventricular global longitudinal strain in patients with type 2 diabetes: Relationship with microvascular damage and glycemic control

Autor:	Giovanni Antonio Silverii, Loira Toncelli, Lorenzo Casatori, Rachele Bossini, Filippo Nannelli, Laura Pala, Edoardo Mannucci
Rok vydání:	2022
Předmět:	Glycated Hemoglobin Ventricular Dysfunction Left Cross-Sectional Studies Nutrition and Dietetics Diabetes Mellitus Type 2 Endocrinology Diabetes and Metabolism Humans Medicine (miscellaneous) Glycemic Control Cardiology and Cardiovascular Medicine Biomarkers Ventricular Function Left
Zdroj:	Nutrition, Metabolism and Cardiovascular Diseases. 32:994-1000
ISSN:	0939-4753
DOI:	10.1016/j.numecd.2022.01.014
Popis:	Type 2 Diabetes mellitus (T2DM) is associated with a higher risk of Heart Failure; Left Ventricular (LV) diastolic dysfunction is often considered the first marker of Diabetic cardiomyopathy; however, early preclinical LV systolic dysfunction has also been observed by means of echocardiographic measurement of strain. This study is aimed at assessing determinants of impaired strain and diastolic ventricular dysfunction in patients with T2DM.Cross-sectional study, performed on a consecutive series of patients with T2DM aged 30-80 years, BMI40 kg/mIn patients with T2DM, a reduced left ventricular global longitudinal strain appears to be independently associated with impaired glucose control and autonomic neuropathy, regardless of microvascular complications.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8885b93d5a1635194a6384542fe65e83 https://doi.org/10.1016/j.numecd.2022.01.014 Zobrazit plný text záznamu Full Text from ScienceDirect