Changing head model extent affects finite element predictions of transcranial direct current stimulation distributions
| Autor: | Rosalind J. Sadleir, Munish Chauhan, Benjamin L. Schwartz, Aprinda Indahlastari |
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| Rok vydání: | 2016 |
| Předmět: |
Models
Anatomic medicine.medical_treatment Finite Element Analysis 0206 medical engineering Biomedical Engineering 02 engineering and technology Transcranial Direct Current Stimulation Article Bone and Bones 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Cerebellum medicine Range (statistics) Humans Gray Matter Electrodes Simulation Physics Human head Transcranial direct-current stimulation Skull Electric Conductivity Mechanics Magnetic Resonance Imaging White Matter 020601 biomedical engineering Finite element method Apex (geometry) Data set Anisotropy Head (vessel) Head Current density Algorithms 030217 neurology & neurosurgery Forecasting |
| Zdroj: | Journal of Neural Engineering. 13:066006 |
| ISSN: | 1741-2552 1741-2560 |
| Popis: | Objective. In this study, we determined efficient head model sizes relative to predicted current densities in transcranial direct current stimulation (tDCS). Approach. Efficiency measures were defined based on a finite element (FE) simulations performed using nine human head models derived from a single MRI data set, having extents varying from 60%–100% of the original axial range. Eleven tissue types, including anisotropic white matter, and three electrode montages (T7–T8, F3-right supraorbital, Cz–Oz) were used in the models. Main results. Reducing head volume extent from 100% to 60%, that is, varying the model's axial range from between the apex and C3 vertebra to one encompassing only apex to the superior cerebellum, was found to decrease the total modeling time by up to half. Differences between current density predictions in each model were quantified by using a relative difference measure (RDM). Our simulation results showed that was the least affected (a maximum of 10% error) for head volumes modeled from the apex to the base of the skull (60%–75% volume). Significance. This finding suggested that the bone could act as a bioelectricity boundary and thus performing FE simulations of tDCS on the human head with models extending beyond the inferior skull may not be necessary in most cases to obtain reasonable precision in current density results. |
| Databáze: | OpenAIRE |
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